Snap-8

Acetyl Octapeptide-3 (sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2) is a synthetic peptide that is an analog of Acetyl Hexapeptide-8. It was designed based on the structure of the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex, a key protein assembly in neurotransmitter release.

The peptide's design rationale relates to its potential interaction with the SNARE complex at the neuromuscular junction. It is studied for its effects on modulating neurotransmitter release and the intensity of muscle cell contraction in experimental models.

Acetyl Octapeptide-3 is investigated for its activity related to the SNARE complex, which is essential for the fusion of synaptic vesicles with the presynaptic membrane and subsequent neurotransmitter release.

Published nonclinical literature relevant to this material's molecular targets and experimental models is listed below for independent review. Findings involving other preparations or experimental systems should not be attributed to this research material.

This material is supplied solely for in vitro and other nonclinical laboratory research. It is not for human or veterinary use, consumption, administration, therapeutic use, or diagnostic use.

Laboratory Handling

Handle only in an appropriately equipped laboratory using applicable institutional procedures, personal protective equipment, and the storage conditions shown for the material. The purchaser is responsible for study design, handling controls, disposal, and regulatory compliance.

Research Limitations

Published observations involving other preparations, experimental systems, or study populations do not establish the identity, performance, or suitability of this research material for any particular experiment.