PT-141

PT-141, also known as Bremelanotide, is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH) and a metabolite of Melanotan II. It functions as a melanocortin receptor agonist. Its mechanism of action, which involves central nervous system pathways, is distinct from compounds like phosphodiesterase-5 (PDE5) inhibitors that act via peripheral vascular mechanisms.

Refer to the cited literature for research concerning this material's molecular characteristics and experimental targets.

Published nonclinical literature relevant to this material's molecular targets and experimental models is listed below for independent review. Findings involving other preparations or experimental systems should not be attributed to this research material.

This material is supplied solely for in vitro and other nonclinical laboratory research. It is not for human or veterinary use, consumption, administration, therapeutic use, or diagnostic use.

Laboratory Handling

Handle only in an appropriately equipped laboratory using applicable institutional procedures, personal protective equipment, and the storage conditions shown for the material. The purchaser is responsible for study design, handling controls, disposal, and regulatory compliance.

Research Limitations

Published observations involving other preparations, experimental systems, or study populations do not establish the identity, performance, or suitability of this research material for any particular experiment.