KissPeptin-10

Kisspeptin-10 is a peptide consisting of the C-terminal 10 amino acids of the longer kisspeptin peptides (kisspeptin-54, -14, and -13). All kisspeptin variants are derived from the same precursor protein and share a common C-terminal sequence, and Kisspeptin-10 retains the biological activity of the longer forms.

Kisspeptin-10 acts through binding to and activation of the kisspeptin receptor KISS1R (also known as GPR54), a G-protein coupled receptor. KISS1R is expressed on GnRH neurons in the hypothalamus, as well as in other tissues such as the pituitary, gonads, and placenta.

Published nonclinical literature relevant to this material's molecular targets and experimental models is listed below for independent review. Findings involving other preparations or experimental systems should not be attributed to this research material.

This material is supplied solely for in vitro and other nonclinical laboratory research. It is not for human or veterinary use, consumption, administration, therapeutic use, or diagnostic use.

Laboratory Handling

Handle only in an appropriately equipped laboratory using applicable institutional procedures, personal protective equipment, and the storage conditions shown for the material. The purchaser is responsible for study design, handling controls, disposal, and regulatory compliance.

Research Limitations

Published observations involving other preparations, experimental systems, or study populations do not establish the identity, performance, or suitability of this research material for any particular experiment.